Importance

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Abstract

A method for determining a characteristic of an analyte in a biological sample comprising: directing broadband light by means of a sensing light path at the biological sample; receiving the broadband light reflected from the biological sample; directing the broadband light by means of the reference light path at a reflecting device; and receiving the broadband light reflected from the reflecting device. The method also includes: interfering the broadband light reflected from the biological sample and the broadband light reflected from the reflecting device; detecting the broadband light resulting from the interfering to provide an interference signal indicative of a first intensity measurement corresponding to a first depth in the biological sample; and varying an effective light path length of at least one of the reference light path and the sensing light path to define a second depth in the biological sample. The method further includes: detecting the broadband light resulting from the interfering, to provide another interference signal indicative a second intensity measurement corresponding to the second depth; and determining the characteristic based on the intensity measurements.

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First Claim