Thienodibenzoazulene compounds as tumor necrosis factor inhibitors
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United States of America Patent
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Issued Date -
Aug 4, 2005
app pub date -
Mar 25, 2005
filing date -
May 17, 2000
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Abandoned
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Abstract
The present invention relates to the dibenzoazulene compounds represented by formula I as well as to their pharmaceutical preparations for the inhibition of tumor necrosis factor alpha (TNF-.alpha.) and interleukine 1 (IL-1) in mammals at all diseases and conditions where these mediators are excessively secreted. The compounds of the present invention also demonstrate an analgetic action and can be used to relieve pain.
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