Methods and compositions for use in the treatment of mutant receptor tyrosine kinase driven cellular proliferative diseases
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United States of America Patent
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Issued Date -
Aug 4, 2005
app pub date -
Dec 9, 2004
filing date -
Dec 11, 2003
priority date (Note) -
Abandoned
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Abstract
Methods for treating a subject suffering from a cellular proliferative disease characterized by the presence of a mutant receptor tyrosine kinase are provided. In practicing the subject methods, an effective amount of a CDK4 inhibitor, either alone or in combination with at least one of an inhibitor of the mutant receptor tyrosine kinase and an MEK inhibitor, is administered to the subject. Also provided are compositions, including pharmaceutical formulations and kits thereof, for practicing the subject methods.
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