Raman spectroscopy for monitoring drug-eluting medical devices
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United States of America Patent
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Issued Date -
Aug 4, 2005
app pub date -
Jan 9, 2004
filing date -
Jan 9, 2004
priority date (Note) -
Abandoned
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Abstract
The present invention provides low-resolution Raman spectroscopic systems and methods for in situ monitoring of drug-eluting devices in a lumen of a subject. A preferred system can employ multi-mode radiation in making in situ Raman spectroscopic measurements of the lumen and/or device. For example, a system can include a light source such as a multi-mode laser, and a light detector to measure spectral patterns and differentiates spectral features of drugs released in a target region. Drug-release curves can be extrapolated or otherwise predicted using the Raman spectrum taken during or subsequent to device insertion and/or activation.
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