High speed spectral domain functional optical coherence tomography and optical doppler tomography for in vivo blood flow dynamics and tissue structure

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United States of America Patent

PATENT NO 7359062
APP PUB NO 20050171438A1
SERIAL NO

11009717

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Abstract

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A system for tomographic imaging includes a source of at least partially coherent radiation, a frequency-swept laser source and an interferometer. The radiation in the interferometer is phase modulated at a modulation frequency for elimination of DC and autocorrelation noises as well as the mirror image. The interference fringes of the radiation backscattered from the sample into the interferometer are detected to obtain a spectral signal. The spectral signal of the detected backscattered interference fringes is transformed to obtain a location dependent signal at each pixel location in a data window. A tomographic image of the fluid flow in the data window is generated for display and of the structure of the scanned fluid flow sample in the data window from the location dependent signal is generated.

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Patent Owner(s)

Patent OwnerAddress
REGENTS OF THE UNIVERSITY OF CALIFORNIA THE300 LAKESIDE DRIVE 22ND FLOOR OAKLAND CA 94612 UNITED STATES OF AMERICA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Zhongping Irvine, CA 107 2051
Nelson, J Stuart Laguna Niguel, CA 19 2330
Zhang, Jun Irvine, CA 1152 7034

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