Automatic infusion system based on an adaptive patient model

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United States of America Patent

PATENT NO 7491187
SERIAL NO

10508572

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Present invention is a system of blood glucose monitoring and intensive insulin therapy in a ICU for strict maintenance of normoglycemia which reduces intensive care and hospital mortality and morbidity of critically ill adult patients. The findings of present study also reveal factors determining insulin doses needed to maintain normoglycemia as well as the impact of insulin dose versus blood glucose level on the observed outcome benefits have been established. The invention provides a control system that adapts the flow of the insulin infusion based on insulin requirement calculated by blood glucose levels and clinical parameters such as history of diabetes, Body Mass Index, blood glucose level on admission, reason of ICU admission, time in the ICU, type and severity of illness, caloric intake, obesity, drugs affecting insulin sensitivity). This automated insulin monitoring systems significantly reduces the workload and human resource management problems for intensive insulin therapy in patients in the ICU.

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Patent Owner(s)

Patent OwnerAddress
K U LEUVEN RESEARCH & DEVELOPMENTLEUVEN LEUVEN FLEMISH BRABANT

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Aerts, Jean-Marie Haasrode , BE 8 946
Berckmans, Daniel Kessel-lo , BE 9 949
De, Moor Bart Bierbeek , BE 6 683
De, Smet Frank Mechelen , BE 1 657
Pluymers, Bert Westerlo , BE 4 700
Van, Den Berghe Greta Grez-doiceau , BE 5 708

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