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United States of America Patent
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Issued Date -
Aug 18, 2005
app pub date -
Mar 2, 2005
filing date -
Feb 6, 2002
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The present invention relates to a method of assaying for folate in a folate containing sample, wherein at least some of the folate comprises at least one attached glutamate residue. The method comprises subjecting the sample to hydrolysis to release paraminobenzoic acid, p-aminobenzoyl glutamic acid, or a salt thereof; contacting the released paraminobenzoic acid, p-aminobenzoyl glutamic acid, salt or a diazo derivative thereof, with a binding partner thereof; and directly or indirectly detecting the resulting binding partner: paraminobenzoic acid, binding partner: p-aminobenzoyl glutamic acid, or salt or derivative combination. The invention further relates to a kit usable in the method of the invention.
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