Molecular switches and methods for making and using the same
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United States of America Patent
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Jul 23, 2013
Grant Date -
Aug 18, 2005
app pub date -
Mar 10, 2003
filing date -
Mar 11, 2002
priority date (Note) -
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Abstract
The invention provides molecular switches which couple external signals to functionality and to methods of making and using the same. The switches according to the invention can be used, for example, to regulate gene transcription, target drug delivery to specific cells, transport drugs intracellularly, control drug release, provide conditionally active proteins, perform metabolic engineering, and modulate cell signaling pathways. Libraries comprising the switches and expression vectors and host cells for expressing the switches are also provided.
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