Device for in vivo delivery of bioactive agents and method of manufacture thereof
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United States of America Patent
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Aug 18, 2015
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app pub date -
Sep 9, 2004
filing date -
Nov 17, 2000
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Abstract
The present invention consists of an implantable structural element for in vivo controlled delivery of bioactive active agents to a situs in a body. The implantable structural element may be configured as an implantable prosthesis, such as an endoluminal stent, cardiac valve, osteal implant or the like, which serves a dual function of being prosthetic and a carrier for a bioactive agent. Control over elution of the bioactive agents occurs through a plurality of cantilever-like cover members which prevent drug elution until an endogenous or exogenous stimulus causes the cover members to open and permit drug elution.
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