Method and spectral/imaging device for optochemical sensing with plasmon-modified polarization

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United States of America Patent

APP PUB NO 20050186565A1
SERIAL NO

11117001

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Abstract

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The invention discloses a method and spectral-imaging device for optochemical sensing with plasmon-modified multiband fluorescence polarization and with plasmon-modified polarization phase shift changes of a light beam reflected and/or passed through a total internal reflection conducting structure. The optochemical sensing is performed for molecules placed nearby the conducting structure and being excited by surface plasmon resonance (SPR) to lower excited state (LES) and/or to higher excited states (HES). The invention also describes the spectral imaging device with an improved sensitivity of several orders of magnitude. The disclosed method and imaging device may find applications in clinical diagnostics, pharmaceutical screening, biomedical research, biochemical-warfare detection and other diagnostic techniques. The device can be used in bio-chip and micro-array technologies, flowcytometer, fiber optic and other types of diagnostic devices.

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Patent Owner(s)

Patent OwnerAddress
AMERICAN ENVIRONMENTAL SYSTEMS INC8444 HIGH RIDGE ROAD ELLICOTT CITY MD 21043

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Malak, Henryk Ellicott City, MD 23 1139

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