Production of chimeric mouse-human antibodies with specificity to human tumor antigens

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United States of America Patent

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10263182

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Abstract

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Gene expression elements and their use in production of chimeric antibodies with human constant regions and murine variable regions, and mouse human chimeric antibodies having specificity to human tumor cells, methods of their production, and their use.

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Patent Owner(s)

Patent OwnerAddress
XOMA TECHNOLOGY LTD2 CHURCH STREET CLARENDON HOUSE HAMILTON HM11

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Better, Marc D Los Angeles, CA 27 499
Chang, Changtung Paul Chatsworth, CA 3 18
Horwitz, Arnold H Los Angeles, CA 27 1224
Lei, Shau-Ping Los Angeles, CA 16 1304
Robinson, Randy R Los Angeles, CA 22 2541

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