Inducing cellular immune responses to p53 using peptide and nucleic acid compositions
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United States of America Patent
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Issued Date -
Sep 8, 2005
app pub date -
Feb 7, 2005
filing date -
Jun 17, 1998
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Abstract
This invention uses our knowledge of the mechanisms by which antigen is recognized by T cells to identify and prepare p53 epitopes, and to develop epitope-based vaccines directed towards p53-bearing tumors. More specifically, this application communicates our discovery of pharmaceutical compositions and methods of use in the prevention and treatment of cancer.
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