In vitro methods of producing and identifying immunoglobulin molecules in eukaryotic cells

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20050196755A1
SERIAL NO

10465808

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Abstract

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The present invention relates to a high efficiency method of expressing immunoglobulin molecules in eukaryotic cells. The invention is further drawn to a method of producing immunoglobulin heavy and light chain libraries, particularly using the trimolecular recombination method, for expression in eukaryotic cells. The invention further provides methods of selecting and screening for antigen-specific immunoglobulin molecules, and antigen-specific fragments thereof. The invention also provides kits for producing, screening and selecting antigen-specific immunoglobulin molecules. Finally, the invention provides immunoglobulin molecules, and antigen-specific fragments thereof, produced by the methods provided herein.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
UNIVERSITY OF ROCHESTERROCHESTER, NY461

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Smith, Ernest S Ontario, NY 36 391
Zauderer, Maurice Pittsford, NY 45 455

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