Methods for modulation of immune responses using humanized immunoglobulins reactive with B7-1 molecules
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United States of America Patent
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May 12, 2009
Grant Date -
Sep 22, 2005
app pub date -
Nov 12, 2004
filing date -
Feb 12, 1999
priority date (Note) -
Expired
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Abstract
The invention relates to humanized anti-B7-2 and anti-B7-1 antibodies, wherein each comprise a variable region of non-human origin and at least a portion of an immunoglobulin of human origin. The invention also pertains to methods of treatment for various autoimmune diseases, transplant rejection, inflammatory disorders and infectious diseases by administering humanized anti-B7-2 and/or anti-B7-1 antibodies.
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