Method of preparing pharmaceutical dosage forms containing multiple active ingredients
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United States of America Patent
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N/A
Issued Date -
Sep 22, 2005
app pub date -
Sep 25, 2003
filing date -
Oct 4, 2002
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
A method for the preparation of pharmaceutical dosage forms comprising multiple powdered active ingredients, in a preferred embodiment, said method comprising the steps of mixing said active ingredients and at least one chosen excipient so as to obtain a powdered mixture; compacting said powdered mixture in a roller-compactor apparatus to obtain a compacted product; breaking and sieving said compacted product to a chosen mesh size to obtain similar sized granules; preferably dry mixing said granules with at least on chosen excipient so as to obtain a granular mixture; forming said granular mixture into unitary dosage forms.
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