Histamine-3 receptor antagonists

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United States of America Patent

APP PUB NO 20050245543A1
SERIAL NO

11107457

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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This invention is directed to a compound of the formula I 1 as defined herein, or a pharmaceutically acceptable salt thereof; a pharmaceutical composition containing a compound of formula I, a method of treatment of a disorder or condition that may be treated by antagonizing histamine H3 receptors, the method comprising administering to a mammal in need of such treatment a compound of formula I as described above, and a method of treatment of a disorder or condition selected from the group consisting of depression, mood disorders, schizophrenia, anxiety disorders, Alzheimer's disease, attention-deficit disorder (ADD), attention-deficit hyperactivity disorder (ADHD), psychotic disorders, sleep disorders, obesity, dizziness, epilepsy, motion sickness, respiratory diseases, allergy, allergy-induced airway responses, allergic rhinitis, nasal congestion, allergic congestion, congestion, hypotension, cardiovascular disease, diseases of the GI tract, hyper and hypo motility and acidic secretion of the gastro-intestinal tract, the method comprising administering to a mammal in need of such treatment a compound of formula I as described above.

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Patent Owner(s)

Patent OwnerAddress
PFIZER INC235 EAST 42ND STREET NEW YORK NY 10017

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Howard, Harry R Bristol, CT 26 227
Wlodecki, Bishop Preston, CT 9 86

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