Preparation for the prophylaxis of restenosis
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United States of America Patent
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Jul 6, 2010
Grant Date -
May 12, 2005
app pub date -
Dec 20, 2001
filing date -
Mar 26, 2001
priority date (Note) -
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status (Latency Note)
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Abstract
The invention relates to a preparation for restenosis prevention. The preparations for restenosis prevention known as yet do not reach sufficient active agent concentrations in the affected sections of the vascular walls as higher doses cause undesirable side effects. The present invention is a preparation to which at least one antihyperplastic agent is added that has a distribution ratio between butanol and water ≧0.5. The lipophilic active agent is absorbed by the vascular wall fast and in sufficient quantity. The preparation may be a liquid that can pass through capillaries and may contain a contrast agent so that the active agent is transferred into the vascular wall without any additional effort while the usually required contrast radiograms are taken. The preparation may also be applied to a catheter.
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