Mutant glutamine synthetase and method for producing amino acids
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United States of America Patent
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app pub date -
Jun 28, 2005
filing date -
Nov 30, 2001
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Abandoned
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Abstract
Amino acids, such as L-glutamine, L-arginine, L-tryptophan, L-histidine and L-glutamate are produced using a bacterium belonging to the genus Escherichia harboring a mutant glutamine synthetase in which the tyrosine amino acid residue corresponding to position 397 in a wild type glutamine synthetase is replaced with any of amino acid residues, preferably with phenylalanine.
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