Attenuated vaccine useful for immunizations against Coccidioides spp. infections
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United States of America Patent
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Issued Date -
Nov 24, 2005
app pub date -
Apr 7, 2005
filing date -
Apr 7, 2004
priority date (Note) -
Abandoned
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Abstract
The present invention provides compositions of attenuated fungal mutants and polynucleotide sequences used to transform fungal strains by gene deletions or gene replacements, which are useful for generating an immunological response in human and animals and in therapeutic applications of infections due to pathogenic Coccidioides spp. fungi, such as C. immitis or C. posadasii.
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