Methods to make and use antibodies of improved cross-reactivity
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United States of America Patent
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Issued Date -
Dec 8, 2005
app pub date -
Mar 1, 2005
filing date -
Mar 2, 2004
priority date (Note) -
Abandoned
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Abstract
The present invention relates to methods of generating antibodies of improved cross-reactivity against antigens that give rise to immunotypic variations in infectious organisms. The methods include immunizing animals with multiple immunogen preparations that are derived from the antigen of interest. The present invention also includes methods of use of the antibodies of improved cross-reactivity, and assays and kits for employing such methods.
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