US Patent Application No: 2005/0277,129

Number of patents in Portfolio can not be more than 2000

APOE genetic markers associated with age of onset of Alzheimer's disease

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Abstract

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Haplotypes in the APOE gene associated with age of onset of Alzheimer's Disease are disclosed. Compositions and methods for detecting and using these APOE haplotypes in a variety of clinical applications are disclosed. Such applications include articles of manufacture comprising compounds effective in delaying the age of onset of AD in individuals at risk for developing AD and having one of these APOE haplotypes, methods and kits for predicting the age of onset of AD in an individual at risk for developing AD based upon his/her haplotype profile, and methods for delaying the age of onset of AD in individuals at risk for developing AD based upon their haplotype profile.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
PGXHEALTH, LLCNEWTON, MA2

International Classification(s)

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  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Aerssens, Jeroen Nieuwrode, BE 16 19
Athanasiou, Maria Derby, CT 18 6
Brain, Carlos Somerville, MA 14 6
Cohen, Nadine Warren, NJ 16 19
Dain, Bradley Hamden, CT 14 6
Denton, R Rex Madison, CT 21 24
Judson, Richard S Guilford, CT 23 95
Ozdemir, Vural Long Beach, CA 13 5
Reed, Carol R Bethany, CT 14 6

Cited Art Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (1)
* 2004/0267,458 Methods for obtaining and using haplotype data 8 2001
 
DUKE UNIVERSITY (1)
* 5,508,167 Methods of screening for Alzheimer's disease 51 1994
 
YALE UNIVERSITY (1)
* 5,972,614 Genome anthologies for harvesting gene variants 20 1997
 
GENAISSANCE PHARMACEUTICALS, INC. (1)
* 2005/0026,117 System and method for the management of genomic data 1 2004
 
PGXHEALTH, LLC (4)
* 2005/0255,488 NTRK1 genetic markers associated with age of onset of Alzheimer's Disease 0 2004
* 2005/0255,495 SLC5A7 genetic markers associated with age of onset of Alzheimer's disease 0 2004
* 2006/0154,265 LDLR genetic markers associated with age of onset of Alzheimer's Disease 0 2005
* 2005/0255,498 APOC1 genetic markers associated with age of onset of Alzheimer's Disease 0 2005
* Cited By Examiner

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
Zinfandel Pharmaceuticals, Inc. (3)
8,815,508 Method of identifying disease risk factors 0 2009
8,846,315 Disease risk factors and methods of use 0 2011
9,102,666 Methods and drug products for treating Alzheimer's disease 0 2012
 
THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (1)
* 2006/0228,728 Genetic basis of Alzheimer's disease and diagnosis and treatment thereof 5 2006
 
PGXHEALTH, LLC (4)
* 2005/0255,488 NTRK1 genetic markers associated with age of onset of Alzheimer's Disease 0 2004
* 2005/0255,495 SLC5A7 genetic markers associated with age of onset of Alzheimer's disease 0 2004
* 2006/0154,265 LDLR genetic markers associated with age of onset of Alzheimer's Disease 0 2005
* 2005/0255,498 APOC1 genetic markers associated with age of onset of Alzheimer's Disease 0 2005
* Cited By Examiner