Method of treating lower urinary tract disorders

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United States of America Patent

APP PUB NO 20050282799A1
SERIAL NO

11124580

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to a method of treating at least one symptom of a lower urinary tract disorder in a subject in need of treatment wherein the symptom is selected from the group consisting of urinary frequency, urinary urgency, urinary urge incontinence, nocturia and enuresis. The method comprises administering to a subject in need of treatment a therapeutically effective amount of a compound that has 5-HT.sub.3 receptor antagonist activity and NorAdrenaline Reuptake Inhibitor (NARI) activity. The invention further relates to a method of treating at least one symptom of a lower urinary tract disorder in a subject in need of treatment wherein the symptom is selected from the group consisting of urinary frequency, urinary urgency, urinary urge incontinence, nocturia and enuresis, comprising coadministering to said subject a first amount of a 5-HT.sub.3 antagonist and a second amount of a NARI, wherein the first and second amounts together comprise a therapeutically effective amount or are each present in a therapeutically effective amount.

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Patent Owner(s)

Patent OwnerAddress
DYNOGEN PHARMACEUTICALS INC52 SECOND AVENUE WALTHAM MA 02451

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fraser, Matthew O Apex, NC 11 212
Landau, Steven B Wellesley, MA 48 273
Miller, Cheryl L Natick, MA 8 80

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