Isolating biological modulators from biodiverse gene fragment libraries
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United States of America Patent
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Aug 4, 2005
filing date -
May 5, 1999
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Abandoned
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Abstract
The present invention provides a method for identifying a modulator or mediator of a biological activity, which activity includes antigenicity and or immunogenicity, said method comprising the step of: (i) producing a gene fragment expression library derived from defined nucleotide sequence fragments; and (ii) assaying the expression library for at least an amino acid sequence derived from step (i) for a biological activity wherein that activity is different from any activity the amino acid sequence may have in its native environment.
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