Cytomodulating conjugates of members of specific binding pairs
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United States of America Patent
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app pub date -
Sep 13, 2005
filing date -
Apr 23, 1991
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Abandoned
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Abstract
Novel conjugates are provided comprising a moiety capable of specifically binding to a target cell joined to a selective moiety for binding to an endogenous effector agent, capable of causing cell inactivation or cytotoxicity. Example of conjugates are a ligand for a surface membrane protein, e.g. IL-2 receptor, joined to an .alpha.-galactosyl epitope, or a polysaccharide A or B antigen. The conjugates may be used to specifically destroy cells associated with a pathogenic condition.
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