Transgenic circulating endothelial cells

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United States of America Patent

SERIAL NO

10948344

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Abstract

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A process is provided for expanding the population of endothelial cells obtained from peripheral blood which can be transformed with a vector comprising a DNA sequence encoding a preselected bioactive polypeptide. The resulting transgenic endothelial cells are useful to biocompatibilize implantable medical devices or can be used directly, as for gene therapy.

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Patent Owner(s)

Patent OwnerAddress
REGENTS OF THE UNIVERSITY OF MINNESOTA450 MCNAMARA ALUMNI CENTER 200 OAK STREET S E MINNEAPOLIS MN 55455-2070

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hebbel, Robert P North Oaks, MN 2 62
Lin, Yi St. Paul, MN 122 1239
Lollar, John S Decatur, GA 34 728

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