Stabilization of biologically active proteins with mixtures of polysaccharides and amino acid based compounds

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United States of America Patent

APP PUB NO 20060024346A1
SERIAL NO

10901784

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Abstract

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The invention provides heat stable aqueous solutions or gels comprising a biologically active protein and a stabilizing effective amount of a mixture of a polysaccharide and an amino acid based compound. The invention also discloses stabilized solutions or gels suitable for use in an implantable drug delivery device at body temperature, and a device containing the stabilized solution or gels.

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Patent Owner(s)

Patent OwnerAddress
BATTELLE MEMORIAL INSTITUTEDEPT K1-53 P O BOX 999 RICHLAND WA 99352

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Alavattam, Sreedhara Columbus, OH 27 234
Brody, Richard S Worthington, OH 33 309
Fountain, William M Columbus, OH 4 16
Jones, Randy L Delaware, OH 11 59

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