Methods and compositions for detecting cancer using components of the U2 spliceosomal particle
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United States of America Patent
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Issued Date -
Mar 30, 2006
app pub date -
Sep 21, 2005
filing date -
Sep 21, 2004
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Abandoned
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Abstract
The present invention relates to cancer-associated proteins and nucleic acids that encode or bind specifically to cancer-associated proteins, which represent markers for cancer detection. Specifically, the invention provides a family of methods and compositions for detecting cancer, for example, breast cancer, in an individual using components of the U2 spliceosomal particle. A target cancer-associated protein may be detected, for example, by reacting the sample with a labeled binding moiety, for example, a labeled antibody capable of binding specifically to the protein. The invention also provides kits useful in the detection of cancer in an individual.
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