Methods and compositions for enhancing cartilage repair

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United States of America Patent

SERIAL NO

11223856

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Abstract

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The invention relates to methods of enhancing repair of a cartilage and/or inducing formation of a cartilage by administering a cell, which expresses a factor of the T-box family, which includes inter-alia the brachyury. In another embodiment, the invention relates to an engineered cell, which is transfected with a vector comprising a nucleic acid sequence encoding a factor of the T-box family, thereby expressing a factor of the T-box family. In another embodiment, the invention relates to compositions comprising a vector, which comprises a nucleic acid sequence encoding a factor of the T-box family and in another embodiment the composition-comprising cell that expresses a factor of the T-box family, which includes inter-alia the brachyury.

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Patent Owner(s)

Patent OwnerAddress
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM91390 JERUSALEM

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gazit, Dan Jerusalem, IL 42 523
Gross, Gerhard Braunschweig, DE 54 480
Hoffmann, Andrea Hannover, DE 8 83
Pelled, Gadi Rishon-LeZion, IL 30 403
Turgeman, Gadi Jerusalem, IL 12 117
Zilberman, Yoram Jerusalem, IL 5 66

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