Process for the reduction of (S)-2-amino-6-propionamido-4,5,6,7-tetrahydrobenzo-thiazole

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United States of America Patent

APP PUB NO 20060069263A1
SERIAL NO

11233096

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Abstract

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A process is disclosed for the reduction of (S)-2-amino-6-propionamido-4,5,6,7-tetrahydrobenzothiazole, which comprises reacting (S)-2-amino-6-propionamido-4,5,6,7-tetrahydrobenzothiazole with a borane reagent in the presence of suitable organic solvent to yield (S)-2-amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazole base, which may be converted to an acid addition salt thereof. The process provided herein can be easily, conveniently and inexpensively scaled-up.

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Patent Owner(s)

Patent OwnerAddress
CHEMAGIS LTDISRAEL BRAQUE BONET AIRPORT CITY NORTHERN DISTRICT

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Arad, Oded Rehovot, IL 47 263
Brand, Michael RaAnana, IL 76 1136
Gribun, Irina Bat Yam, IL 6 51
Kaspi, Joseph Givatayim, IL 64 303
Salman, Ada Ramat Gan, IL 4 32
Shiffer, Meital Tel Aviv, IL 2 28
Shookrun, Moty Petach-Tikva, IL 7 55

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