Process for the preparation of zonisamide
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United States of America Patent
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Issued Date -
Apr 20, 2006
app pub date -
May 20, 2005
filing date -
May 20, 2004
priority date (Note) -
Abandoned
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Abstract
The present invention provides an improved process for the preparation of zonisamide or a derivative thereof comprising (a) reacting 1,2-benzisoxazole-3-methane-sulfonic acid with a halogenating agent in a first organic solvent to provide benzisoxazole methane sulfonyl halide; and, (b) reacting benzisoxazole methane sulfonyl halide with an amine in a second organic solvent to form zonisamide or a derivative thereof.
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