Gene shuffling by template switching
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United States of America Patent
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Issued Date -
May 11, 2006
app pub date -
Jul 11, 2003
filing date -
Jul 23, 2002
priority date (Note) -
Abandoned
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Abstract
The present invention provides a new approach to creating novel polynucleotide sequences by point mutation and recombination in vitro of a set of parental sequences. The new polynucleotide sequences can be useful in themselves or they can be used for the templated synthesis of polymers, e.g. polypeptides composed of .alpha.-amino acids as occurring naturally in protein synthesis or polymers comprised of .beta.-amino acids or other building blocks as described (Templated molecules).
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