Process for the preparation of crystalline form II of clarithromycin
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United States of America Patent
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Issued Date -
May 25, 2006
app pub date -
Nov 1, 2005
filing date -
Nov 1, 2004
priority date (Note) -
Abandoned
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Abstract
A process for preparing Form II crystals of clarithromycin is provided comprising (a) treating clarithromycin with a carboxylic acid in an organic solvent to provide a clarithromycin acid salt; and, (b) heating the clarithromycin acid salt at a temperature capable of providing Form II crystals of clarithromycin.
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