Viruses and virus-like particles for multiple antigen and target display

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20060121468A1
SERIAL NO

10519114

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Abstract

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The present invention relates to the display of antigenic or allergenic components along with a tissue-targeting component on viruses or virus-like particles. Capsid protein genes are recombinantly modified to contain the specified components then expressed within a host organism, such as yeasts, bacteria, or algae, and allowed to spontaneously form active virus particles or virus-like particles. The recombinant complexes (virus or virus-like particle) can then be purified or used in situ as a therapeutic tool for disease or allergy prevention. The expression of multivalent and multifunctional components to increase the immunogenicity of the recombinant complexes, especially on oral administration, is provided.

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Patent Owner(s)

Patent OwnerAddress
ADVANCED BIONUTRITION CORPORATION7155 COLUMBIA GATEWAY DRIVE COLUMBIA MD 21046

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Allnutt, F C Thomas Glenwood, MD 10 173
Kyle, David J Catonsville, MD 33 1341

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