Bilayer tablets of oxcarbazepine for controlled delivery and a process of preparation thereof
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United States of America Patent
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N/A
Issued Date -
Jun 29, 2006
app pub date -
Dec 21, 2005
filing date -
Dec 29, 2004
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
Bilayer tablet comprising an immediate release first layer comprising an effective amount of oxcarbazepine and at least one pharmaceutically acceptable excipients and a controlled release second layer comprising an effective amount of oxcarbazepine and pharmaceutically acceptable excipients wherein the total amount of oxcarbazepine impurities is less than or equal to about 2% by weight. A process for preparation of controlled release bilayer tablets is capable of delivering oxcarbazepine from one layer immediately followed by a controlled delivery of oxcarbazepine from a matrix forming layer, and a process for preparation of oxcarbazepine bilayer tablets. Bilayer tablets of oxcarbazepine, which maintain a therapeutically effective blood concentration of oxcarbazepine with once a day administration.
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