Protein modification
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United States of America Patent
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Issued Date -
Jun 29, 2006
app pub date -
Oct 17, 2003
filing date -
Oct 17, 2002
priority date (Note) -
Abandoned
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Abstract
The present invention relates to a method for changing the half-life of a glycosylated compound by the modification of its O-linked carbohydrates. This modification is preferably carried out enzymatically and aimed at extending the half-life of the compound. Both in vivo and in vitro modification protocols may be used.
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