Methods and compositions for screening for altered cellular phenotypes
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United States of America Patent
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app pub date -
Feb 24, 2006
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May 12, 1998
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Abandoned
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Abstract
The invention relates to methods and compositions useful for screening for altered cellular phenotypes using an inducible expression system to enrich for and detect the altered phenotypes and, more particularly, relates to screening libraries of candidate bioactive agents, for example, nucleic acids and peptides, in cells using an regulatable expression system to enrich for a subpopulation of cells having an altered phenotype due to the presence of a candidate bioactive agent.
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