Transdifferentiation of cells and tissues
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United States of America Patent
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Issued Date -
Jul 20, 2006
app pub date -
Mar 17, 2003
filing date -
Mar 18, 2002
priority date (Note) -
Abandoned
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Abstract
Method for carrying out transdifferentiation of non-pancreatic cells to pancreatic cells involving the provision of a pancreas specific transcription factor and an activating means such as VP16 of Herpes simplex virus to non-pancreatic cells. The methods and materials provided by the invention may be used to treat pancreatic disorders, in particular disorders caused by a loss of properly functioning pancreas such as pancreatic cancer and diabetes.
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