Methods for reduced renal uptake of protein conjugates

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United States of America Patent

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11341431

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Abstract

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Kidney uptake of antibody fragment conjugates and protein conjugates in patients is reduced by administration to the patient of one or more compounds selected from the group consisting of D-lysine, poly-D-lysine, or poly-L-lysine, or pharmaceutically acceptable salts or carboxyl derivatives thereof.

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Patent Owner(s)

Patent OwnerAddress
CENTER FOR MOLECULAR MEDICINE AND IMMUNOLOGYONE BRUCE STREET NEWARK NJ 07103-2763 UNITED STATES OF AMERICA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Behr, Thomas M Bloomfield, NJ 6 8
Goldenberg, David M Mendham, NJ 527 13665

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