Oral sustained-release pharmaceutical composition of indapamide, production and use thereof
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United States of America Patent
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N/A
Issued Date -
Aug 17, 2006
app pub date -
Feb 17, 2005
filing date -
Feb 17, 2005
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The present invention relates to an oral sustained-release pharmaceutical composition of indapamide and a process for producing the foregoing pharmaceutical composition. The pharmaceutical composition comprises indapamide in the amount 0.2% to 4% (w/w) of the composition, a hydrophilic polymer in the amount 10% to 30% (w/w) of the composition, a dry binding agent in the amount 2% to 20% (w/w) of the composition, and an erosion modifier in the amount 40% to 80% (w/w) of the composition. The present invention also relates to a method for delivering indapamide to a patient in need of indapamide-related therapies, which comprises administering to the patient a therapeutically effective amount of a sustained-release pharmaceutical composition in accordance with the present invention.
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