Genetic polymorphisms as predictive diagnostics for adverse drug reactions (adr) and drug efficacy

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United States of America Patent

APP PUB NO 20060204962A1
SERIAL NO

10544049

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention provides diagnostic methods and kits including oligo and/or polynucleotides or derivatives, including as well antibodies determining whether a human subject is at risk of getting adverse drug reaction after statin therapy or whether the human subject is a high or low responder or a good a or bad metabolizer of statins. The invention provides further diagnostic methods and kits including antibodies determining whether a human subject is at risk for a cardiovascular disease. Still further the invention provides polymorphic sequences and other genes.

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Patent Owner(s)

Patent OwnerAddress
SIEMENS HEALTHCARE DIAGNOSTICS GMBH65760 ESCHBORN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kallabis, Harald Koln, DE 13 162
Schmitz, Gerd Sinzing, DE 35 353
Schwers, Stephan Koln, DE 15 30
Stropp, Udo Haan, DE 26 244

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