Compounds binding to p-selectin

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United States of America Patent

APP PUB NO 20060217294A1
SERIAL NO

10524172

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Abstract

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The present invention relates to derivatives of compounds which bind selectively to the adhesion molecule human P-selectin, and particularly to such derivatives which comprise a peptide moiety or a functional equivalent of said peptide moiety and are represented by X(A.sub.x).sub.mA.sub.3A.sub.1A.sub.2A.sub.1Y. In addition, the invention relates to methods for preparing such compounds, to the use of such compounds in therapeutic or diagnostic methods and in pharmaceutical compositions, to binding molecules binding to said compounds and to a method for determining whether a compound is capable of binding to P-selectin.

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Patent Owner(s)

Patent OwnerAddress
ASTELLAS PHARMA EUROPE B VELISABETHHOF 19 LEIDERDORP 2353EW

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Appeldoorn, Chantal Catharina Maria Leiden, NL 7 8
Biessen, Erik Anna Leonardus Leiden, NL 7 8
Kuiper, Johan Leiden, NL 9 15
Molenaar, Thomas Jacobus Maria Leiden, NL 6 3
Van, Berkel Theodorus Josephus Cornelis Leiden, NL 11 94

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