NELL-1 enhanced bone mineralization
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United States of America Patent
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Aug 17, 2010
Grant Date -
Oct 12, 2006
app pub date -
Mar 28, 2006
filing date -
Oct 5, 1999
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Abstract
This invention pertains to the discovery that the human NELL-1 gene induces or upregulates bone mineralization. The NELL-1 gene or gene product thus provides a convenient target for screening for modulators of bone mineralization. In addition, NELL-1 can be used to facilitate repair of bone fractures and/or to generally increase bone density.
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