Immunomodulating compositions and methods for use in the treatment of human autoimmune diseases
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United States of America Patent
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N/A
Issued Date -
Oct 26, 2006
app pub date -
Mar 30, 2006
filing date -
Mar 31, 2005
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
A composition and method for treating an autoimmune condition are disclosed. The composition includes of an immunomodulating compound composed of a central amino acid core having a plurality of chemical attachment groups, and a plurality of antigenic peptides which are (i) associated with an auto-immune disorder and (ii) attached to the core groups with the same N-terminus to C-terminus orientation. The compound is carried in a pharmaceutically acceptable carrier. An exemplary compound has an octomeric polylysine core and eight antigenic peptides, such as the peptides identified by SEQ ID NOS: 1-11, attached thereto. The compound is effective in treating an autoimmune disorder, by administering to a subject in need of the treatment, a pharmaceutically effective amount of the compound.
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