Importance

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Abstract

A novel compound represented by the following formula (1) or a salt thereof [wherein R.sup.1, R.sup.5, R.sup.6, R.sup.7, and R.sup.8 represent hydrogen atom, a halogen atom, hydroxyl group, an alkyl group, an alkenyl group and the like; X.sup.1 . . . X.sup.2 represents --CH(R.sup.2)--CH(R.sup.3)--, --CH(R.sup.2)--CH(R.sup.3)--CH(R.sup.4)--, --C(R.sup.2).dbd.C(R.sup.3)--, or --C(R.sup.2).dbd.C(R.sup.3)--CH(R.sup.4)--(R.sup.2, R.sup.3, and R.sup.4 represent hydrogen atom, or an alkyl group); A.sup.1, A.sup.11, A.sup.2, and A.sup.21 represent hydrogen atom, or an alkyl group; Y represents --CH(A.sup.3)-, --CH(A.sup.3)-C(A.sup.4)(A.sup.41)-, --CH(A.sup.3)-C(A.sup.4)(A.sup.41)-C(A.sup.5)(A.sup.51)-, or a single bond (A.sup.3, A.sup.4, A.sup.41, A.sup.5, and A.sup.51 represent hydrogen atom, or an alkyl group), and Z represents hydroxyl group, or --N(A.sup.6)(A.sup.61)(A.sup.6 represents hydrogen atom, or an alkyl group, and A.sup.61 represents hydrogen atom, an alkyl group, a substituted alkyl group and the like)], having an action of potently inhibiting phosphorylation of myosin regulatory light chain.

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First Claim