Stable ophthalmic oil-in-water emulsions with Omega-3 fatty acids for alleviating dry eye
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United States of America Patent
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Issued Date -
Nov 9, 2006
app pub date -
May 3, 2006
filing date -
Mar 18, 2003
priority date (Note) -
Abandoned
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Abstract
An ophthalmic composition includes oil globules dispersed in an aqueous phase. The globules include a surfactant component, a polar oil component that includes an Omega-3 fatty acid and a viscosity modifying agent. The surfactant to oil ratio produces an average size of globules of about 0.1 microns or less. The viscosity is at least as viscous as 0.25% 800K sodium hyaluronate. The composition can be used for treatment of dry eye. The compositions are stable and can have anti-microbial activity sufficient for use as contact lens disinfecting solutions.
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