Preparation of sevoflurane with negligible water content
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United States of America Patent
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Issued Date -
Nov 16, 2006
app pub date -
Apr 18, 2006
filing date -
Apr 18, 2005
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
Provided is a sevoflurane anesthetic product which can remain substantially undegraded after long periods of storage, as well as a method for preparing the product. The product comprises sevoflurane in a glass container having a water content of less than 130 ppm. The method comprises drying sevoflurane having a water content of greater than 130 ppm to a water content les than 130 ppm. A preferred method of drying comprises contacting a sevoflurane composition having a water content of greater than 130 ppm with alumina-containing molecular sieves such that the water content is reduced to less than 130 ppm.
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