Tri-functional nanospheres
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United States of America Patent
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Issued Date -
Nov 23, 2006
app pub date -
May 24, 2005
filing date -
May 23, 2005
priority date (Note) -
Abandoned
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Abstract
Trifunctional nanoparticles have excellent fluorescence, magnetism, and cell recognition, which can be easily manipulated, tracked, and conveniently used to capture target cells. The surface-immobilized molecules of the TFNs might be optionally changed on demand for the purposes of bioanalysis, biomedical imaging, diagnosis, and the combinatorial screening of drugs. The nanoparticle is formed from a mesoporous polymer; a magnetic material adhering to the mesoporous polymer; a fluorescent dye adhering to the mesoporous polymer; and a biomaterial coupled to the mesoporous polymer, where the mesoporous polymer has been treated with hydrazine, and the biomaterial has been treated with an oxidizing agent.
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