Mono-lysine salts of azole compounds

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United States of America Patent

APP PUB NO 20060264406A1
SERIAL NO

11416322

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Mono-lysine salts of triazole compounds having a secondary or tertiary hydroxy group are provided. More particularly, the new water-soluble triazole antifungal mono-lysine salt compounds, or solvates thereof, are provided having the general formula I: wherein A in formula I represents the non-hydroxy portion of a triazole antifungal compound of the type containing a secondary or tertiary hydroxyl group. R and R.sup.1 in formula I can each be a hydrogen atom or an alkyl group having one to six carbon atoms. The novel water-soluble azole compounds are useful for the treatment of fungal infections and can be administered orally, topically and parenterally.

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Patent Owner(s)

Patent OwnerAddress
EISAI CO LTDTOKYO TOKYO METROPOLIS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Chung-Pin H Madison, CT 18 143
Fakes, Michael G Belle Mead, NJ 5 43
Gao, Qi Wallingford, CT 83 483
Kiau, Susanne North Brunswick, NJ 3 5
Pendri, Yadagiri R South Glastonbury, CT 10 24
Vakkalagadda, Blisse North Brunswick, NJ 1 3

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