Construction of knockdown animal by transferring double-stranded rna expression vector
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United States of America Patent
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Issued Date -
Dec 7, 2006
app pub date -
Oct 29, 2003
filing date -
Oct 29, 2002
priority date (Note) -
Abandoned
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Abstract
This invention relates to a target gene-knockdown animal and an animal model for disease in which mRNA of an endogenous target gene is disrupted via formation of double-stranded RNA for the target gene and a method for producing the animals. Also, this invention relates to a ds-RNA expression vector used for such method and an animal cell having such vector introduced therein.
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