Production of foreign nucleic acids and polypeptides in sprout systems
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United States of America Patent
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Apr 6, 2010
Grant Date -
Dec 7, 2006
app pub date -
Feb 13, 2006
filing date -
Nov 12, 2002
priority date (Note) -
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Abstract
The present invention provides systems and methods for producing a nucleic acid or protein in transgenic sprouted seedlings or sprouted seedlings engineered to transiently express a nucleic acid or protein of interest. The sprouted seedlings of the invention are grown in a contained, regulatable environment, wherein expression of a pharmaceutically active protein is controlled by an exogenously inducible promoter or a viral promoter. The sprouted seedlings may be eaten live or preferably harvested live to preserve the maximal biological activity of the nucleic acid or protein.
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